Fetal and maternal endocrine responses to experimental intrauterine infection in rhesus monkeys

MG Gravett, GJ Haluska, MJ Cooka, MJ Novy - American journal of …, 1996 - Elsevier
OBJECTIVE: Our purpose was to describe the temporal and quantitative relationships
among intrauterine infection, fetal-placental steroid biosynthesis, and preterm labor in a
nonhuman primate model. STUDY DESIGN: On approximately day 130 of gestation (term
167 days) chronically instrumented rhesus monkeys (Macaca mulatta) were infected with
106 colony-forming units of group B streptococci either by intraamniotic (n= 4) or
choriodecidual (n= 2) inoculation. As controls, four additional chronically instrumented …