Enhanced oxidative stress in hypertrophic cardiomyopathy
PP Dimitrow, A Undas, P Wołkow, W Tracz… - Pharmacological …, 2009 - Springer
PP Dimitrow, A Undas, P Wołkow, W Tracz, JS Dubiel
Pharmacological reports, 2009•SpringerElevated plasma levels of inflammation and endothelial dysfunction markers have been
reported in patients with hypertrophic car diomyopathy (HCM). The aim of the current study
was to determine whether HCM is associated with enhanced oxidative stress. We enrolled
54 HCM patients with sinus rhythm, including 21 subjects with a left ventricular outflow tract
(LVOT) obstruction (gra dient> 30 mmHg), and 54 age-and sex-matched controls without
cardiovascular diseases. Serum levels of 8-isoprostaglandin F2 a (8-iso-PGF 2α), a stable …
reported in patients with hypertrophic car diomyopathy (HCM). The aim of the current study
was to determine whether HCM is associated with enhanced oxidative stress. We enrolled
54 HCM patients with sinus rhythm, including 21 subjects with a left ventricular outflow tract
(LVOT) obstruction (gra dient> 30 mmHg), and 54 age-and sex-matched controls without
cardiovascular diseases. Serum levels of 8-isoprostaglandin F2 a (8-iso-PGF 2α), a stable …
Abstract
Elevated plasma levels of inflammation and endothelial dysfunction markers have been reported in patients with hypertrophic car diomyopathy (HCM). The aim of the current study was to determine whether HCM is associated with enhanced oxidative stress. We enrolled 54 HCM patients with sinus rhythm, including 21 subjects with a left ventricular outflow tract (LVOT) obstruction (gra dient> 30 mmHg), and 54 age-and sex-matched controls without cardiovascular diseases. Serum levels of 8-isoprostaglandin F2 a (8-iso-PGF 2α), a stable marker of oxidative stress, were determined.
Springer