Plasma leptin is associated with insulin resistance independent of age, body mass index, fat mass, lipids, and pubertal development in nondiabetic adolescents

KC Huang, RCY Lin, N Kormas, LT Lee… - International journal of …, 2004 - nature.com
KC Huang, RCY Lin, N Kormas, LT Lee, CY Chen, TP Gill, ID Caterson
International journal of obesity, 2004nature.com
OBJECTIVE: The rising epidemic worldwide in overweight and obese children requires
urgent attention. Leptin has been found to be associated with body weight control and
possibly affects insulin sensitivity. Since insulin resistance is associated with obesity in
adults and possibly in adolescents, we set out to investigate the association of plasma leptin
level with various anthropometric indices, body fat mass (FM), lipids, and insulin resistance
(IR) index in nondiabetic adolescents. DESIGN: A cross-sectional study from three high …
Abstract
OBJECTIVE: The rising epidemic worldwide in overweight and obese children requires urgent attention. Leptin has been found to be associated with body weight control and possibly affects insulin sensitivity. Since insulin resistance is associated with obesity in adults and possibly in adolescents, we set out to investigate the association of plasma leptin level with various anthropometric indices, body fat mass (FM), lipids, and insulin resistance (IR) index in nondiabetic adolescents.
DESIGN: A cross-sectional study from three high schools in Taipei City in Taiwan.
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