Community-associated MRSA: what makes them special?

M Otto - International Journal of Medical Microbiology, 2013 - Elsevier
While infections with methicillin-resistant Staphylococcus aureus (MRSA) were traditionally
restricted to the hospital setting, novel MRSA strains emerged over the last two decades that
have the capacity to infect otherwise healthy people outside of the hospital setting. These
community-associated (CA-) MRSA strains combine methicillin resistance with enhanced
virulence and fitness. Interestingly, CA-MRSA strains emerged globally and from different
backgrounds, indicating that the “trade-off” between maintaining sufficient levels of …