[HTML][HTML] Glycogen-targeting subunits and glucokinase differentially affect pathways of glycogen metabolism and their regulation in hepatocytes
R Yang, L Cao, R Gasa, MJ Brady, AD Sherry… - Journal of Biological …, 2002 - ASBMB
Overexpression of the glucose-phosphorylating enzyme glucokinase (GK) or members of
the family of glycogen-targeting subunits of protein phosphatase-1 increases hepatic
glucose disposal and glycogen synthesis. This study was undertaken to evaluate the
functional properties of a novel, truncated glycogen-targeting subunit derived from the
skeletal muscle isoform GM/R Gl and to compare pathways of glycogen metabolism and
their regulation in cells with overexpressed targeting subunits and GK. When overexpressed …
the family of glycogen-targeting subunits of protein phosphatase-1 increases hepatic
glucose disposal and glycogen synthesis. This study was undertaken to evaluate the
functional properties of a novel, truncated glycogen-targeting subunit derived from the
skeletal muscle isoform GM/R Gl and to compare pathways of glycogen metabolism and
their regulation in cells with overexpressed targeting subunits and GK. When overexpressed …