Treatment of progressive multifocal leukoencephalopathy with interleukin 7

KB Alstadhaug, T Croughs, S Henriksen… - JAMA …, 2014 - jamanetwork.com
Importance No reliable treatment options are known for progressive multifocal
leukoencephalopathy with underlying immunodeficiency. We describe successful
compassionate use of recombinant human interleukin 7 in a patient with idiopathic CD4+ T-
cell lymphocytopenia. Observations After the diagnoses of progressive multifocal
leukoencephalopathy and idiopathic CD4+ T-cell lymphocytopenia were established, a 61-
year-old man was treated with recombinant human interleukin 7 on November 1, 2012 …