[HTML][HTML] A novel role of neuregulin in skeletal muscle: neuregulin stimulates glucose uptake, glucose transporter translocation, and transporter expression in muscle …
Neuregulins regulate the expression of acetylcholine receptor genes and induce
development of the neuromuscular junction in muscle. In studying whether neuregulins
regulate glucose uptake in muscle, we analyzed the effect of a recombinant neuregulin, r
heregulin-β1-(177–244)(HRG), on L6E9 muscle cells, which express the neuregulin
receptors ErbB2 and ErbB3. L6E9 responded acutely to HRG by a time-and concentration-
dependent stimulation of 2-deoxyglucose uptake. HRG-induced stimulation of glucose …
development of the neuromuscular junction in muscle. In studying whether neuregulins
regulate glucose uptake in muscle, we analyzed the effect of a recombinant neuregulin, r
heregulin-β1-(177–244)(HRG), on L6E9 muscle cells, which express the neuregulin
receptors ErbB2 and ErbB3. L6E9 responded acutely to HRG by a time-and concentration-
dependent stimulation of 2-deoxyglucose uptake. HRG-induced stimulation of glucose …
