Wnt signaling cascades activate morphogenetic programs that range from cell migration and
proliferation to cell fate determination and stem cell renewal. These pathways enable cells to
translate environmental cues into the complex cellular programs that are needed to organize
tissues and build organs. Wnt signaling is essential for renal development; however, the
specific molecular underpinnings involved are poorly understood. Recent research has
revealed an unexpected intersection between Wnt signaling and polycystic kidney disease …