[HTML][HTML] Potential impact of microarray diagnosis of T cell–mediated rejection in kidney transplants: The INTERCOM study
We previously developed a microarray-based test for T cell-mediated rejection (TCMR) in a
reference set of 403 biopsies. To determine the potential impact of this test in clinical
practice, we undertook INTERCOM, a prospective international study of 300 indication
biopsies from 264 patients (ClinicalTrials. gov NCT01299168). Biopsies from six centers—
Baltimore, Barcelona, Edmonton, Hannover, Manchester and Minneapolis—were analyzed
by microarrays, assigning TCMR scores by an algorithm developed in the reference set and …
reference set of 403 biopsies. To determine the potential impact of this test in clinical
practice, we undertook INTERCOM, a prospective international study of 300 indication
biopsies from 264 patients (ClinicalTrials. gov NCT01299168). Biopsies from six centers—
Baltimore, Barcelona, Edmonton, Hannover, Manchester and Minneapolis—were analyzed
by microarrays, assigning TCMR scores by an algorithm developed in the reference set and …