Classicallydescribedasacell'sabilitytodifferentiateinto all3germlayers—mesoderm, ectoderm,
andendoderm—pluripotencyhaslongbeentheelusivecoreofg… that, if properly controlled,
could lead to organandtissueregenerationinhumans. In2006, Takahashi and Yamanaka and
colleagues1 advanced biomedical science with the discovery that pluripotency could be
induced in adult cells using just 4 embryonic transcription factors. Their method for creating
so-called induced pluripotent stem cells (iPSCs) was straightforward for many laboratories …