Epstein-Barr virus (EBV) provides a useful model to study cellular immunity to a genetically
stable, persistent human virus. Different sets of proteins expressed during EBV's lytic and
cell transforming infections induce qualitatively different cellular immune responses. The
factors governing immunodominance hierarchies and the biological effectiveness of these
different responses are now being revealed. Analysis of infectious mononucleosis (IM), a
clinical syndrome that can arise during primary EBV infection, has allowed the evolution of …