Childhood course of lung function in survivors of bronchopulmonary dysplasia
M Filippone, G Bonetto, E Cherubin, S Carraro… - Jama, 2009 - jamanetwork.com
Results. The BPD group showed consistent lung function tracking, indicated by no
significant change in mean z score between ages 2 years (VmaxFRC z score,− 1.48; 95%
confidence interval [CI],− 2.19 to− 0.77), 9 years (z score for forced expiratory volume in 1
second [FEV1],− 1.74, 95% CI,− 2.27 to− 1.21), and 15 years (FEV1 z score,− 1.71; 95% CI,−
2.60 to− 0.82; P=. 62)(TABLE). There was no change in mean z score for spirometry
variables between ages 9 and 15 years in the control groups. Values for FEV1 were …
significant change in mean z score between ages 2 years (VmaxFRC z score,− 1.48; 95%
confidence interval [CI],− 2.19 to− 0.77), 9 years (z score for forced expiratory volume in 1
second [FEV1],− 1.74, 95% CI,− 2.27 to− 1.21), and 15 years (FEV1 z score,− 1.71; 95% CI,−
2.60 to− 0.82; P=. 62)(TABLE). There was no change in mean z score for spirometry
variables between ages 9 and 15 years in the control groups. Values for FEV1 were …