[HTML][HTML] An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets
Genome biology, 2003•Springer
We report a database of genes responsive to the Myc oncogenic transcription factor. The
database Myc Target Gene prioritizes candidate target genes according to experimental
evidence and clusters responsive genes into functional groups. We coupled the prioritization
of target genes with phylogenetic sequence comparisons to predict c-Myc target binding
sites, which are in turn validated by chromatin immunoprecipitation assays. This database is
essential for the understanding of the genetic regulatory networks underlying the genesis of …
database Myc Target Gene prioritizes candidate target genes according to experimental
evidence and clusters responsive genes into functional groups. We coupled the prioritization
of target genes with phylogenetic sequence comparisons to predict c-Myc target binding
sites, which are in turn validated by chromatin immunoprecipitation assays. This database is
essential for the understanding of the genetic regulatory networks underlying the genesis of …
Abstract
We report a database of genes responsive to the Myc oncogenic transcription factor. The database Myc Target Gene prioritizes candidate target genes according to experimental evidence and clusters responsive genes into functional groups. We coupled the prioritization of target genes with phylogenetic sequence comparisons to predict c-Myc target binding sites, which are in turn validated by chromatin immunoprecipitation assays. This database is essential for the understanding of the genetic regulatory networks underlying the genesis of cancers.
Springer