Multiple fractures associated with long-term sodium heparin therapy
MD Jaffe, PW Willis - Jama, 1965 - jamanetwork.com
SODIUM HEPARIN, because of its anticoagulant and lipid-clearing effects, has gained
widespread acceptance for the long-term treatment of coronary artery disease. Except for
bleeding, usually the result of an excesssive therapeutic action, there have been few side
effects reported. A previously unrecognized possible complication of heparin therapy is
detailed here. A patient is presented in whom multiple fractures of vertebrae and ribs
occurred in the last two months of a 13-month course of therapy with sodium heparin …
widespread acceptance for the long-term treatment of coronary artery disease. Except for
bleeding, usually the result of an excesssive therapeutic action, there have been few side
effects reported. A previously unrecognized possible complication of heparin therapy is
detailed here. A patient is presented in whom multiple fractures of vertebrae and ribs
occurred in the last two months of a 13-month course of therapy with sodium heparin …