Developing a new definition and assessing new clinical criteria for septic shock: for the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis …

M Shankar-Hari, GS Phillips, ML Levy, CW Seymour… - Jama, 2016 - jamanetwork.com
Importance Septic shock currently refers to a state of acute circulatory failure associated with
infection. Emerging biological insights and reported variation in epidemiology challenge the
validity of this definition. Objective To develop a new definition and clinical criteria for
identifying septic shock in adults. Design, Setting, and Participants The Society of Critical
Care Medicine and the European Society of Intensive Care Medicine convened a task force
(19 participants) to revise current sepsis/septic shock definitions. Three sets of studies were …