Context Colorectal cancer is the third most common form of cancer and the fourth most
frequent cause of cancer deaths worldwide. The association between cigarette smoking and
colorectal cancer has been inconsistent among studies. Objective To clarify the association
of cigarette smoking and colorectal cancer, we performed a comprehensive literature search
and a meta-analysis of observational studies considering both incidence and mortality. Data
Sources We performed a literature search using PubMed, ISI Web of Science (Science …