Sirolimus use and risk of cutaneous squamous cell carcinoma (SCC) in solid organ transplant recipients (SOTRs)

MM Asgari, ST Arron, EM Warton… - Journal of the American …, 2015 - Elsevier
Background Little is known about the use of sirolimus for primary prevention of cutaneous
squamous cell carcinoma (SCC) among solid organ transplant recipients (SOTRs).
Objective We examined the association between sirolimus exposure and incident SCC risk
among SOTRs within Kaiser Permanente Northern California. Methods Using a
retrospective cohort of all Kaiser Permanente Northern California members given a
diagnosis of SOTR from 2000 through 2010, we evaluated incident posttransplantation SCC …