Therapeutic approaches to asthma–chronic obstructive pulmonary disease overlap syndromes
PJ Barnes - Journal of Allergy and Clinical Immunology, 2015 - Elsevier
The recognition that there are some patients with features of asthma and chronic obstructive
pulmonary disease (COPD) has highlighted the need to develop more specific treatments for
these clinical phenotypes. Some patients with COPD have predominantly eosinophilic
inflammation and might respond to high doses of inhaled corticosteroids and newly
developed specific antieosinophil therapies, including blocking antibodies against IL-5, IL-
13, IL-33, and thymic stromal lymphopoietin, as well as oral chemoattractant receptor …
pulmonary disease (COPD) has highlighted the need to develop more specific treatments for
these clinical phenotypes. Some patients with COPD have predominantly eosinophilic
inflammation and might respond to high doses of inhaled corticosteroids and newly
developed specific antieosinophil therapies, including blocking antibodies against IL-5, IL-
13, IL-33, and thymic stromal lymphopoietin, as well as oral chemoattractant receptor …
