A glucose-controlled insulin-delivery system: semisynthetic insulin bound to lectin
M Brownlee, A Cerami - Science, 1979 - science.org
M Brownlee, A Cerami
Science, 1979•science.orgA stable, biologically active glycosylated insulin derivative that is complementary to the
major combining site of concanavalin A has been synthesized. Hormone release is
proportional to the quantity of glucose present. Glucose regulation of exogenous insulin
delivery could have important applications in the therapy of diabetes mellitus.
major combining site of concanavalin A has been synthesized. Hormone release is
proportional to the quantity of glucose present. Glucose regulation of exogenous insulin
delivery could have important applications in the therapy of diabetes mellitus.
A stable, biologically active glycosylated insulin derivative that is complementary to the major combining site of concanavalin A has been synthesized. Hormone release is proportional to the quantity of glucose present. Glucose regulation of exogenous insulin delivery could have important applications in the therapy of diabetes mellitus.
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