Lipid and fatty acid profile of the retina, retinal pigment epithelium/choroid, and the lacrimal gland, and associations with adipose tissue fatty acids in human subjects

L Bretillon, G Thuret, S Grégoire, N Acar, C Joffre… - Experimental eye …, 2008 - Elsevier
Accumulation of lipids within Bruch's membrane (BrM) and between BrM and retinal pigment
epithelium (RPE) accounts for one of the biological changes associated with normal aging
and may contribute to the development of age-related maculopathies. The origin of these
lipids is still being actively investigated. The relative contribution of plasma lipids and lipids
coming from the neural retina remains a matter of controversy. Low-density lipoproteins
(LDLs) have been reported to significantly participate in the retina's lipid supply, after active …