[HTML][HTML] Phenotype, distribution and alloreactive properties of memory T cells from cynomolgus monkeys
O Nadazdin, S Boskovic, T Murakami… - American Journal of …, 2010 - Elsevier
The high frequency of memory T cells present in primates is thought to represent a major
barrier to tolerance induction in transplantation. Therefore, it is crucial to characterize these
memory T cells and determine their functional properties. High numbers of memory T cells
were detected in peripheral blood and all lymphoid tissues except lymph nodes, which were
essentially the site of naïve T cells. The majority of CD8+ memory T cells were effector
memory cells located in the blood and bone marrow while most CD4+ memory T cells were …
barrier to tolerance induction in transplantation. Therefore, it is crucial to characterize these
memory T cells and determine their functional properties. High numbers of memory T cells
were detected in peripheral blood and all lymphoid tissues except lymph nodes, which were
essentially the site of naïve T cells. The majority of CD8+ memory T cells were effector
memory cells located in the blood and bone marrow while most CD4+ memory T cells were …
