Importance Animal models suggest that reduced cerebral blood flow (CBF) is one of the
most enduring physiological deficits following concussion. Despite this, longitudinal studies
documenting serial changes in regional CBF following human concussion have yet to be
performed. Objective To longitudinally assess the recovery of CBF in a carefully selected
sample of collegiate athletes and compare time course of CBF recovery with that of cognitive
and behavioral symptoms. Design, Setting, and Participants A cohort of collegiate football …