A multivariate analysis of risk factors for the air-trapping asthmatic phenotype as measured by quantitative CT analysis
A Busacker, JD Newell Jr, T Keefe, EA Hoffman… - Chest, 2009 - Elsevier
Background Patients with severe asthma have increased physiologically measured air
trapping; however, a study using CT measures of air trapping has not been performed. This
study was designed to address two hypotheses:(1) air trapping measured by multidetector
CT (MDCT) quantitative methodology would be a predictor of a more severe asthma
phenotype; and (2) historical, clinical, allergic, or inflammatory risk factors could be identified
via multivariate analysis. Methods MDCT scanning of a subset of Severe Asthma Research …
trapping; however, a study using CT measures of air trapping has not been performed. This
study was designed to address two hypotheses:(1) air trapping measured by multidetector
CT (MDCT) quantitative methodology would be a predictor of a more severe asthma
phenotype; and (2) historical, clinical, allergic, or inflammatory risk factors could be identified
via multivariate analysis. Methods MDCT scanning of a subset of Severe Asthma Research …