Paired inspiratory/expiratory volumetric thin-slice CT scan for emphysema analysis: comparison of different quantitative evaluations and pulmonary function test

J Zaporozhan, S Ley, R Eberhardt, O Weinheimer… - Chest, 2005 - Elsevier
Purpose: The aim of the study was to use three-dimensional high-resolution CT scan data
sets in inspiration and expiration for the quantitative evaluation of emphysema. Using an
advanced dedicated semiautomatic analysis tool, the functional inspiratory/expiratory shifts
of emphysema volume and clusters were quantified. The pulmonary function test (PFT)
served as the clinical “gold standard.” Materials and methods: Thirty-one patients (9 women
and 22 men; mean [±SD] age, 60±8 years) who had severe emphysema due to COPD …