Wheezing and Airflow Obstrurtion during Methacholine Challenge in Children with Cystic Fibrosis and in
I Sanchez, RE Powell, H Pasterkamp - American Review of …, 1993 - atsjournals.org
I Sanchez, RE Powell, H Pasterkamp
American Review of Respiratory Disease, 1993•atsjournals.orgMETHODS We evaluated 10 young CF patients (yCF), 7 males and 3 females, at a mean
age of 5.7 yr (range 4 to 7 yr), who had Shwachman-Kulczycki (SK) scores of 93±5.9
(mean±standard deviation, SO), and 13 older CF patients (oCF), 7 males and 6 females, at a
mean age of 10.5 yr (range 8 to 18 yr), with SK scores of 82±11.5 and baseline FE~ of
82.4±220/0 of predicted. The clinical-radiologic score (SK) ranges from 0 to an optimum of
100 (12). All patients were being followed regularly at the Cystic Fibrosis Clinic, Children's …
age of 5.7 yr (range 4 to 7 yr), who had Shwachman-Kulczycki (SK) scores of 93±5.9
(mean±standard deviation, SO), and 13 older CF patients (oCF), 7 males and 6 females, at a
mean age of 10.5 yr (range 8 to 18 yr), with SK scores of 82±11.5 and baseline FE~ of
82.4±220/0 of predicted. The clinical-radiologic score (SK) ranges from 0 to an optimum of
100 (12). All patients were being followed regularly at the Cystic Fibrosis Clinic, Children's …
METHODS
We evaluated 10 young CF patients (yCF), 7 males and 3 females, at a mean age of 5.7 yr (range 4 to 7 yr), who had Shwachman-Kulczycki (SK) scores of 93±5.9 (mean±standard deviation, SO), and 13 older CF patients (oCF), 7 males and 6 females, at a mean age of 10.5 yr (range 8 to 18 yr), with SK scores of 82±11.5 and baseline FE~ of 82.4±220/0 of predicted. The clinical-radiologic score (SK) ranges from 0 to an optimum of 100 (12). All patients were being followed regularly at the Cystic Fibrosis Clinic, Children's Hospital of Winnipeg. They were not on regular treatment with inhaled steroids, and they had not used bronchodilator therapy within 12 h before the study. All subjects were free of upper or lower respiratory tract illness during 4 wk before the test and had no wheeze at baseline.
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