[HTML][HTML] Emerging influence of the intestinal microbiota during allogeneic hematopoietic cell transplantation: control the gut and the body will follow
MD Docampo, JJ Auletta, RR Jenq - Biology of Blood and Marrow …, 2015 - Elsevier
MD Docampo, JJ Auletta, RR Jenq
Biology of Blood and Marrow Transplantation, 2015•ElsevierThe intestinal microbiota has many critical roles in maintaining gastrointestinal epithelial and
gastrointestinal systemic immune homeostasis. This review provides insight into how
allogeneic hematopoietic cell transplantation (HCT) and its associated complications and
supportive care therapies affect the microbiota. Additionally, the review discusses how
preservation and restoration of the microbiota might be advantageous in decreasing HCT-
related morbidity and mortality.
gastrointestinal systemic immune homeostasis. This review provides insight into how
allogeneic hematopoietic cell transplantation (HCT) and its associated complications and
supportive care therapies affect the microbiota. Additionally, the review discusses how
preservation and restoration of the microbiota might be advantageous in decreasing HCT-
related morbidity and mortality.
Abstract
The intestinal microbiota has many critical roles in maintaining gastrointestinal epithelial and gastrointestinal systemic immune homeostasis. This review provides insight into how allogeneic hematopoietic cell transplantation (HCT) and its associated complications and supportive care therapies affect the microbiota. Additionally, the review discusses how preservation and restoration of the microbiota might be advantageous in decreasing HCT-related morbidity and mortality.
Elsevier