The APACHE III prognostic system: risk prediction of hospital mortality for critically III hospitalized adults

WA Knaus, DP Wagner, EA Draper, JE Zimmerman… - Chest, 1991 - Elsevier
The objective of this study was to refine the APACHE (Acute Physiology, Age, Chronic
Health Evaluation) methodology in order to more accurately predict hospital mortality risk for
critically ill hospitalized adults. We prospectively collected data on 17,440 unselected adult
medical/surgical intensive care unit (ICU) admissions at 40 US hospitals (14 volunteer
tertiary-care institutions and 26 hospitals randomly chosen to represent intensive care
services nationwide). We analyzed the relationship between the patient's likelihood of …