Recently α-chloro fatty aldehydes have been shown to be products of reactive chlorinating
species targeting the vinyl ether bond of plasmalogens utilizing a cell-free system.
Accordingly, the present experiments were designed to show that α-chloro fatty aldehydes
are produced by activated neutrophils and to determine their physiologic effects. A sensitive
gas chromatography-mass spectrometry technique was developed to detect
pentafluorobenzyl oximes of α-chloro fatty aldehydes utilizing negative ion chemical …