[HTML][HTML] Reactive chlorinating species produced by myeloperoxidase target the vinyl ether bond of plasmalogens: identification of 2-chlorohexadecanal
CJ Albert, JR Crowley, FF Hsu, AK Thukkani… - Journal of Biological …, 2001 - ASBMB
Plasmalogens contain a vinyl ether bond linking the sn-1 aliphatic chain to the glycerol
backbone of this predominant phospholipid molecular subclass, which is found in many
mammalian tissues. The present study demonstrates that the vinyl ether bond of
plasmalogens is a molecular target of the reactive chlorinating species produced by
myeloperoxidase. Analysis by thin layer chromatography revealed that reactive chlorinating
species produced by myeloperoxidase target the vinyl ether bond of the plasmalogen …
backbone of this predominant phospholipid molecular subclass, which is found in many
mammalian tissues. The present study demonstrates that the vinyl ether bond of
plasmalogens is a molecular target of the reactive chlorinating species produced by
myeloperoxidase. Analysis by thin layer chromatography revealed that reactive chlorinating
species produced by myeloperoxidase target the vinyl ether bond of the plasmalogen …
