PD-1 blockade in HIV-infected patients with lung cancer: a new challenge or already a strategy?
A Lavolé, A Guihot, M Veyri, O Lambotte… - Annals of …, 2018 - annalsofoncology.org
Volume 29| Issue 4| 2018 doi: 10.1093/annonc/mdx817| 1065 unexpected toxicity occurred
in all patients, except one, patient# 7, who developed a hypereosinophilia then an anterior
uveitis with confusion after three infusions of nivolumab. Cerebrospinal fluid and plasma
examinations confirmed the diagnosis of active neurosyphilis. After nivolumab
discontinuation and penicillin G administration, symptoms completely disappeared. Steroids
were not administrated and nivolumab not restarted while patient remained in partial …
in all patients, except one, patient# 7, who developed a hypereosinophilia then an anterior
uveitis with confusion after three infusions of nivolumab. Cerebrospinal fluid and plasma
examinations confirmed the diagnosis of active neurosyphilis. After nivolumab
discontinuation and penicillin G administration, symptoms completely disappeared. Steroids
were not administrated and nivolumab not restarted while patient remained in partial …