The effects of apolipoprotein B depletion on HDL subspecies composition and function [S]

WS Davidson, A Heink, H Sexmith, JT Melchior… - Journal of lipid …, 2016 - jlr.org
HDL cholesterol (HDL-C) efflux function may be a more robust biomarker of coronary artery
disease risk than HDL-C. To study HDL function, apoB-containing lipoproteins are
precipitated from serum. Whether apoB precipitation affects HDL subspecies composition
and function has not been thoroughly investigated. We studied the effects of four common
apoB precipitation methods [polyethylene glycol (PEG), dextran sulfate/magnesium chloride
(MgCl 2), heparin sodium/manganese chloride (MnCl 2), and LipoSep immunoprecipitation …