Serum vascular endothelial growth factor-D levels in patients with lymphangioleiomyomatosis reflect lymphatic involvement
CG Glasgow, NA Avila, JP Lin, MP Stylianou, J Moss - Chest, 2009 - Elsevier
Background Lymphangioleiomyomatosis (LAM) is a rare multisystem disorder affecting
primarily women of child-bearing age, and characterized by cystic lung destruction, tumors
of the kidney (angiomyolipomas [AMLs]), and involvement of the axial lymphatics (
lymphangioleiomyomas). Patients with LAM experience loss of pulmonary function attributed
to the proliferation of abnormal-appearing smooth muscle-like cells (LAM cells). It is possible
to group the LAM population by the presence or absence of extrapulmonary involvement …
primarily women of child-bearing age, and characterized by cystic lung destruction, tumors
of the kidney (angiomyolipomas [AMLs]), and involvement of the axial lymphatics (
lymphangioleiomyomas). Patients with LAM experience loss of pulmonary function attributed
to the proliferation of abnormal-appearing smooth muscle-like cells (LAM cells). It is possible
to group the LAM population by the presence or absence of extrapulmonary involvement …
