A screening test to identify aldosterone-producing adenoma by measuring plasma renin activity: results in hypertensive patients
K Hiramatsu, T Yamada, Y Yukimura… - Archives of internal …, 1981 - jamanetwork.com
• In an attempt to devise a screening test for aldosterone-producing adenoma (APA) among
hypertensive patients, the serum sodium and potassium levels, plasma renin activity (PRA),
plasma aldosterone concentration, and aldosterone-PRA ratio were measured in 348
patients with hypertension. Nine patients with a substantially elevated aldosterone-PRA ratio
were selected and hospitalized for further investigations. All nine patients were then
recognized by scintigraphy with labeled cholesterol, venography, and surgical excision as …
hypertensive patients, the serum sodium and potassium levels, plasma renin activity (PRA),
plasma aldosterone concentration, and aldosterone-PRA ratio were measured in 348
patients with hypertension. Nine patients with a substantially elevated aldosterone-PRA ratio
were selected and hospitalized for further investigations. All nine patients were then
recognized by scintigraphy with labeled cholesterol, venography, and surgical excision as …