[PDF][PDF] Sugar? No thank you, just a deep breath of oxygen for cancer stem cells

A Viale, GF Draetta - Cell Metabolism, 2015 - cell.com
Cell Metabolism, 2015cell.com
Tumors are metabolically heterogeneous, and subpopulations of tumorigenic cells have
been recently described to rely more on mitochondrial respiration than glycolysis for energy
production. In this issue, Sancho et al.(2015) demonstrate that MYC is a master switch
regulating metabolic programs in different subpopulations of pancreatic tumor cells.
Tumors are metabolically heterogeneous, and subpopulations of tumorigenic cells have been recently described to rely more on mitochondrial respiration than glycolysis for energy production. In this issue, Sancho et al. (2015) demonstrate that MYC is a master switch regulating metabolic programs in different subpopulations of pancreatic tumor cells.
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