[HTML][HTML] Pregnancy alters choline dynamics: results of a randomized trial using stable isotope methodology in pregnant and nonpregnant women
Background: Although biomarkers of choline metabolism are altered by pregnancy, little is
known about the influence of human pregnancy on the dynamics of choline-related
metabolic processes. Objective: This study used stable isotope methodology to examine the
effects of pregnancy on choline partitioning and the metabolic activity of choline-related
pathways. Design: Healthy third-trimester pregnant (n= 26; initially week 27 of gestation) and
nonpregnant (n= 21) women consumed 22% of their total choline intake (480 or 930 mg/d) …
known about the influence of human pregnancy on the dynamics of choline-related
metabolic processes. Objective: This study used stable isotope methodology to examine the
effects of pregnancy on choline partitioning and the metabolic activity of choline-related
pathways. Design: Healthy third-trimester pregnant (n= 26; initially week 27 of gestation) and
nonpregnant (n= 21) women consumed 22% of their total choline intake (480 or 930 mg/d) …
