Feto-placental morphological effects of prenatal exposure to drugs of abuse
S Ortigosa, B Friguls, X Joya, S Martinez… - Reproductive …, 2012 - Elsevier
The aim of the study was to find morphological changes in the feto-placental unit due to
prenatal exposure to drugs of abuse. A blind histomorphometric study was performed using
225 placentas. Based on meconium testing, the fetuses were classified as exposed or
unexposed to opiates, cocaine, cannabis or alcohol. To establish prenatal tobacco
exposure, cotinine in cord blood was analyzed. At the microscopic level a non statistically
significant reduction of placental vascularization was observed in cocaine, opiates and …
prenatal exposure to drugs of abuse. A blind histomorphometric study was performed using
225 placentas. Based on meconium testing, the fetuses were classified as exposed or
unexposed to opiates, cocaine, cannabis or alcohol. To establish prenatal tobacco
exposure, cotinine in cord blood was analyzed. At the microscopic level a non statistically
significant reduction of placental vascularization was observed in cocaine, opiates and …
