Perigestational alcohol consumption induces altered early placentation and organogenic embryo growth restriction by disruption of trophoblast angiogenic factors
GS Gualdoni, MR Ventureira, TA Coll… - Reproductive …, 2021 - Elsevier
Research question Maternal alcohol consumption produces fetal retardation and
malformations, probably associated with placental defects. Does perigestational alcohol
consumption up to organogenesis lead to abnormal placentation and embryo growth
restriction by disrupting the vascular endothelial growth factor (VEGF) system in embryo–
placental development? Design Female mice were treated with 10% ethanol in drinking
water before and up to day 10 of gestation. Control mice received ethanol-free water. After …
malformations, probably associated with placental defects. Does perigestational alcohol
consumption up to organogenesis lead to abnormal placentation and embryo growth
restriction by disrupting the vascular endothelial growth factor (VEGF) system in embryo–
placental development? Design Female mice were treated with 10% ethanol in drinking
water before and up to day 10 of gestation. Control mice received ethanol-free water. After …
