ICAM-1 and VCAM-1 are differentially expressed on blood-retinal barrier cells during experimental autoimmune uveitis
R Dewispelaere, D Lipski, V Foucart, C Bruyns… - Experimental Eye …, 2015 - Elsevier
Adhesion molecules play a central role in leukocyte adhesion to the blood-retinal barrier
(BRB) during uveitis. VCAM-1 expression on the BRB has been already described but
although structurally similar, ICAM-1 has shown in various autoimmunity models to have
distinct role and expression. Here, we induced uveitis in C57Bl/6 mice by adoptive transfer
of semi-purified T cells from IRBP1-20-immunized mice. Using Flow cytometry analysis on
transferred cells and immunofluorescence staining on retina we have studied the …
(BRB) during uveitis. VCAM-1 expression on the BRB has been already described but
although structurally similar, ICAM-1 has shown in various autoimmunity models to have
distinct role and expression. Here, we induced uveitis in C57Bl/6 mice by adoptive transfer
of semi-purified T cells from IRBP1-20-immunized mice. Using Flow cytometry analysis on
transferred cells and immunofluorescence staining on retina we have studied the …
