Critical role of neutrophil extracellular traps (NETs) in patients with Behcet's disease
A Le Joncour, R Martos, S Loyau, N Lelay… - Annals of the rheumatic …, 2019 - Elsevier
Objectives Behçet's disease (BD) is a chronic systemic vasculitis. Thrombosis is a frequent
and life-threatening complication. The pathogenesis of BD is poorly understood and
evidence supporting a role for primed neutrophils in BD-associated thrombotic risk is scant.
To respond to inflammatory insults, neutrophils release web-like structures, known as
neutrophil extracellular traps (NETs), which are prothrombotic. We evaluated the role of
NETs and markers of NETs in BD. Methods Blood samples were collected from patients with …
and life-threatening complication. The pathogenesis of BD is poorly understood and
evidence supporting a role for primed neutrophils in BD-associated thrombotic risk is scant.
To respond to inflammatory insults, neutrophils release web-like structures, known as
neutrophil extracellular traps (NETs), which are prothrombotic. We evaluated the role of
NETs and markers of NETs in BD. Methods Blood samples were collected from patients with …
