Pimozide treatment of tic and Tourette disorders
AK Shapiro, E Shapiro, G Fulop - Pediatrics, 1987 - publications.aap.org
Tourette disorder is a chronic multiple tic condition that begins in childhood and may require
lifelong treatment. Neuroleptics are the most effective and frequently used drugs for the
treatment of both Tourette and tic disorders. Haloperidol was the first neuroleptic drug
approved by the Food and Drug Administration (FDA) for the treatment of adult patients with
Tourette disorder in 1969 and for children in 1978. Its effectiveness in the treatment of tics is
well documented. 1, 2 However, adverse effects limit its usefulness and new drugs that have …
lifelong treatment. Neuroleptics are the most effective and frequently used drugs for the
treatment of both Tourette and tic disorders. Haloperidol was the first neuroleptic drug
approved by the Food and Drug Administration (FDA) for the treatment of adult patients with
Tourette disorder in 1969 and for children in 1978. Its effectiveness in the treatment of tics is
well documented. 1, 2 However, adverse effects limit its usefulness and new drugs that have …