Corneal wound healing in monkeys after repeated excimer laser photorefractive keratectomy
KD Hanna, YM Pouliquen, GO Waring… - Archives of …, 1992 - jamanetwork.com
• Five rhesus monkey eyes underwent repeated argon fluoride (193 nm) excimer laser
myopic photorefractive keratectomy 3 months following an initial ablation that had produced
mild subepithelial haze. At 3 months all eyes had development of a dense subepithelial
opacity and a thickened epithelium (12 cells, 80 μm) with vacuolization of basal cells,
fragmented basement membrane, and a layer of subepithelial fibrosis containing activated
fibroblasts. By 6 months the opacity was clearing; epithelium was thinner (50 μm); …
myopic photorefractive keratectomy 3 months following an initial ablation that had produced
mild subepithelial haze. At 3 months all eyes had development of a dense subepithelial
opacity and a thickened epithelium (12 cells, 80 μm) with vacuolization of basal cells,
fragmented basement membrane, and a layer of subepithelial fibrosis containing activated
fibroblasts. By 6 months the opacity was clearing; epithelium was thinner (50 μm); …
