Characterization of limbal stem cell deficiency by in vivo laser scanning confocal microscopy: a microstructural approach

SX Deng, KD Sejpal, Q Tang, AJ Aldave… - Archives of …, 2012 - jamanetwork.com
Objective To evaluate the cellular changes in the corneal epithelium and surrounding
structures in limbal stem cell deficiency (LSCD) by using in vivo laser scanning confocal
microscopy. Methods This was a prospective comparative study that included 27 eyes of 20
patients with LSCD and 12 eyes of 10 healthy subjects. All subjects underwent slitlamp
examination, and LSCD was classified into 3 groups on the basis of clinical presentation.
Confocal imaging of the central cornea and 4 locations of limbus was performed …