[HTML][HTML] A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells
Purpose Single cell (sc) analyses of key embryonic, fetal and adult stages were performed to
generate a comprehensive single cell atlas of all the corneal and adjacent conjunctival cell
types from development to adulthood. Methods Four human adult and seventeen embryonic
and fetal corneas from 10 to 21 post conception week (PCW) specimens were dissociated to
single cells and subjected to scRNA-and/or ATAC-Seq using the 10x Genomics platform.
These were embedded using Uniform Manifold Approximation and Projection (UMAP) and …
generate a comprehensive single cell atlas of all the corneal and adjacent conjunctival cell
types from development to adulthood. Methods Four human adult and seventeen embryonic
and fetal corneas from 10 to 21 post conception week (PCW) specimens were dissociated to
single cells and subjected to scRNA-and/or ATAC-Seq using the 10x Genomics platform.
These were embedded using Uniform Manifold Approximation and Projection (UMAP) and …