[HTML][HTML] Deciphering mechanism of the herbal formula WuShen in the treatment of postinfarction heart failure
H Qiu, ZY Huang, H Cao, Z Zhang, J Ma, XQ Li… - Phytomedicine, 2022 - Elsevier
Background Numerous clinical studies reported the effectiveness of herbal formula WuShen
(WS) in treating cardiovascular diseases, yet relevant basic research was rarely conducted.
Methods and results Twelve main bioactive compounds of WS decoction were identified
using the ultra-performance liquid chromatography-LTQ-Orbitrap mass spectrometer. A total
of 137 active compounds with 613 targets were predicted by network pharmacology; their
bioinformatic annotation and human microarray data suggested that wounding healing …
(WS) in treating cardiovascular diseases, yet relevant basic research was rarely conducted.
Methods and results Twelve main bioactive compounds of WS decoction were identified
using the ultra-performance liquid chromatography-LTQ-Orbitrap mass spectrometer. A total
of 137 active compounds with 613 targets were predicted by network pharmacology; their
bioinformatic annotation and human microarray data suggested that wounding healing …