Updating the CoFAR grading scale for systemic allergic reactions in food allergy
RS Chinthrajah, SM Jones, EH Kim, SH Sicherer… - Journal of Allergy and …, 2022 - Elsevier
Background Immunotherapy is promising as an efficacious treatment for food allergy. Other
food allergy treatments are also under development. However, adverse allergic events
during treatment, as well as during oral food challenges, are common and reporting is not
standardized. Objective A more nuanced grading scale is needed to create a
comprehensive and universal system to categorize adverse events and their severity for
food allergy clinical trials. Methods Starting with the 2012 Consortium for Food Allergy …
food allergy treatments are also under development. However, adverse allergic events
during treatment, as well as during oral food challenges, are common and reporting is not
standardized. Objective A more nuanced grading scale is needed to create a
comprehensive and universal system to categorize adverse events and their severity for
food allergy clinical trials. Methods Starting with the 2012 Consortium for Food Allergy …
