Oral tolerance and oral immunotherapy for food allergy: evidence for common mechanisms?

W Kazmi, MC Berin - Cellular Immunology, 2023 - Elsevier
Food allergies affect up to 10% of the US population, can be life-threatening, and have a
significant negative impact on quality of life. Delayed dietary introduction of foods in
childhood can hinder the induction of oral tolerance, an active regulatory response to foods
that prevents the development of food allergy. Some children outgrow their food allergies
naturally, while many others have persistent, lifelong food allergy for which there are few
therapeutic options. Oral immunotherapy (OIT) is a therapeutic approach of giving …