SiNiSan alleviates liver injury by promoting hepatic stem cell differentiation via Wnt/β-catenin signaling pathway
W Xu, X Du, J Li, Z Zhang, X Ma, D Luo, M Xiao, Q Sun - Phytomedicine, 2022 - Elsevier
Abstract Background SiNiSan, a Traditional Chinese Medicine containing Radix Bupleuri,
Radix Paeoniae Alba, Fructus Aurantii Immaturus, and Radix Glycyrrhizae, has been shown
to be clinically effective in treating liver damage, its underlying molecular mechanisms
however remains unclear. Purpose The aim of the current study was to understand the
molecular mechanisms of SiNiSan in the treatment of liver damage utilizing mice and cell
culture models. Methods Here, mice were gavaged with 0.2% CCl 4 to obtain acute liver …
Radix Paeoniae Alba, Fructus Aurantii Immaturus, and Radix Glycyrrhizae, has been shown
to be clinically effective in treating liver damage, its underlying molecular mechanisms
however remains unclear. Purpose The aim of the current study was to understand the
molecular mechanisms of SiNiSan in the treatment of liver damage utilizing mice and cell
culture models. Methods Here, mice were gavaged with 0.2% CCl 4 to obtain acute liver …
