Tracer priming the bicarbonate pool

JR Allsop, RR Wolfe, JF Burke - Journal of Applied …, 1978 - journals.physiology.org
JR Allsop, RR Wolfe, JF Burke
Journal of Applied Physiology, 1978journals.physiology.org
We have described a technique whereby the time necessary to reach an equilibrium
enrichment of expired CO2 during a primed-constant infusion of [U-13C] glucose was
shortened from 7 to 8 h to 1 hour or less. We applied the theory of the primed-constant
infusion technique to the bicarbonate pool, with the “constant infusion” of labeled carbon
dioxide originating from oxidation of the infused [13C] glucose rather than from a labeled
infusion of bicarbonate.
We have described a technique whereby the time necessary to reach an equilibrium enrichment of expired CO2 during a primed-constant infusion of [U-13C]glucose was shortened from 7 to 8 h to 1 hour or less. We applied the theory of the primed-constant infusion technique to the bicarbonate pool, with the “constant infusion” of labeled carbon dioxide originating from oxidation of the infused [13C]glucose rather than from a labeled infusion of bicarbonate.
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