Flotillins/cavatellins are differentially expressed in cells and tissues and form a hetero-oligomeric complex with caveolins in vivo: characterization and epitope …

D Volonté, F Galbiati, S Li, K Nishiyama… - Journal of Biological …, 1999 - jbc.org
Caveolae are vesicular organelles that represent a subcompartment of the plasma
membrane. Caveolins and flotillins are two families of mammalian caveolae-associated
integral membrane proteins. However, it remains unknown whether flotillins interact with
caveolin proteins to form a stable caveolar complex or if expression of flotillins can drive
vesicle formation. Here, we examine the cell type and tissue-specific expression of the
flotillin gene family. For this purpose, we generated a novel monoclonal antibody probe that …