[HTML][HTML] LncRNA AK054921 and AK128652 are potential serum biomarkers and predictors of patient survival with alcoholic cirrhosis

Z Yang, RA Ross, S Zhao, W Tu… - Hepatology …, 2017 - journals.lww.com
Alcoholic liver disease (ALD) is one of the leading causes of chronic liver disease. Recent
studies have demonstrated the roles of long noncoding RNAs (lncRNAs) in the
pathogenesis of several disease processes. However, the roles of lncRNAs in patients with
ALD remain unexplored. Global profiling for human lncRNAs from peripheral blood RNA
was performed in a well‐characterized cohort of healthy controls (HC; n= 4), excessive
drinkers (ED) without liver disease (n= 4), and those with alcoholic cirrhosis (AC) with …